Table 3.
Comparison of demographic and clinical characteristics between relatives of dialysis patients and controls
| Variables | Relatives (n = 1062) | Controls (n = 2124) | P Value |
|---|---|---|---|
| Age (y) |
44.0 ± 12.1 |
43.7 ± 12.3 |
0.61 |
| Male (%) |
401 (37.8) |
802 (37.8) |
1.0 |
| Education (≥High School, %) |
810 (76.3) |
1393 (65.8) |
<0.001 |
| Hypertension (%) |
278 (26.3) |
721 (34.0) |
<0.001 |
| Diabetes (%) |
109 (10.3) |
162 (7.7) |
0.02 |
| Overweight (%) |
588 (55.6) |
1182 (55.7) |
1.0 |
| Nephrotoxic medications (%) |
67 (6.4) |
51 (2.4) |
<0.001 |
| Chronic respiratory tract infection (%) |
178 (16.9) |
300 (14.1) |
0.05 |
| Dyslipidemia (%) |
480 (45.2) |
673 (31.7) |
<0.001 |
| eGFR (mL/min/1.73 m2) |
94.0 ± 16.9 |
92.4 ± 18.9 |
0.03 |
| Low eGFR (%) <60 (mL/min/1.73 m2) |
16 (1.5) |
50 (2.4) |
0.12 |
| Albuminuria (%) |
149 (14.4) |
178 (8.4) |
<0.001 |
| CKD (%) | 155 (14.6) | 221 (10.5) | <0.01 |
Note: Data expressed as mean ± standard deviation or number (percentage); Overweight was defined as body mass index >24 kg/m2; Dyslipidemia was defined as present if total cholesterol was ≥ 5.72 mmol/L (220 mg/dL), or if low density lipoprotein was ≥ 3.64 mmol/L (140 mg/dL), or triglyceride was ≥ 1.70 mmol/L (150 mg/dL) or high density lipoprotein was < 0.91 mmol/L (35 mg/dL); Albuminuria was defined as urinary albumin-creatinine ratio ≥ 17 mg/g (1.9 mg/mmoL) for males and 25 mg/g (2.8 mg/mmoL) for females; CKD was defined as decreased kidney function (<60 mL/min/1.73 m2) or albuminuria.
Abbreviations: eGFR, estimated glomerular filtration rate; CKD, chronic kidney disease.