Table 1. Clinicopathological significance of the detergent-soluble cytoplasmic Survivin expression in colorectal cancer.

Factors	Tumor without the detergent-soluble cytoplasmic Survivin (n = 23)		Tumor with the detergent-soluble cytoplasmic Survivin (n = 17)		P value
	No.	%	No.	%
Age (mean ± SD)	65.2±10.9	65.0±8.9
Sex
Male	17	73.9	8	47.1	0.08
Female	6	26.1	9	52.9
Histological grade
Well, Moderately	19	82.6	13	76.5	0.46
Poorly, Muc expression	4	17.4	4	23.5
Size
<50 mm (small)	12	70.1	3	30	<0.05*
>51 mm (large)	5	29.9	7	70
Tumor invasiona
m, sm, mp, ss	19	82.6	10	58.8	0.095
se, si	4	17.4	7	41.2
Lymphatic invasion
Absent	15	65.2	6	35.3	0.061
Present	8	34.8	11	64.7
Venous invasion
Absent	20	87.0	11	64.7	0.100
Present	3	13.0	6	35.3
Lymph node metastasis
Absent	16	69.6	1	5.9	<0.001*
Present	7	30.4	16	94.1
Distant metastasis
Absent	23	100	12	70.6	<0.01*
Present	0	0	5	29.4

^aTumor invasion of mucosa (m), submucosa (sm), muscularis propria (mp), subserosa (ss), penetration of serosa (se), and invasion of adjacent strucures (si).

^*Significant difference.