Figure 4. Photon flux is modulated by the type of anesthesia.

a) PE_max and AUC were decreased under Ketamine/Xylazine conditions but not different for Pentobarbital compared to Isoflurane. b, c) Representative time activity curves showing the anesthesia dependent signal behavior leading to delayed time-to-peak for Ketamine/Xylazine, but no clear difference between Isoflurane and Pentobarbital anesthesia. (* statistically significant difference with p≤0.05 to standard protocol 150 mg/kg post-Iso in post hoc comparison with Sidak correction).