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. 2013 Feb 6;8(2):e55628. doi: 10.1371/journal.pone.0055628

Figure 7. Induction of nuclear grooves after knockdown of BRG1 does not depend on intact actin filaments.

Figure 7

(A) Matched individual confocal sections of representative fields of cells before and after treatment with Latrunculin B at 0.2 µg/ml for 30 minutes. Actin filaments were detected with Phalloidin-TRITC (red), while nuclei were counterstained with the DNA dye DRAQ5 (blue). Size bar 10 µm. (B) Quantification of nuclear grooves in control cells and cells treated with Latrunculin B. The means for three counts of at least 100 nuclei scored for grooves under each condition are presented +/− standard deviation. * represents p<0.05, *** represents p<0.005 as determined by Student’s t-test.