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. 2013 Feb 6;8(2):e56009. doi: 10.1371/journal.pone.0056009

Table 2. Demographic, clinical, and laboratory data for patients with and without NASH.

NASH no NASH P-value Test
N 22 15
Fibrosis (any) 22 (100%) 10 (67%) 0.015 Chi
Advanced fibrosis 3 (14%) 3 (20%) 0.667 FE
Diabetes 8 (36%) 5 (33%) 0.872 Chi
Female 16 (73%) 9 (60%) 0.647 Chi
Caucasian 19 (86%) 12 (80%) 0.951 Chi
Age 49±9 47±11 0.596 2T
BMI 49±11 46±9 0.421 MW
Hyperlipidemia 12 (54%) 11 (73%) 0.417 Chi
Hypertension 15 (68%) 11 (73%) 0.801 Chi
AST (U/L) 23±6.4 22±7.4 0.760 2T
ALT (U/L) 35±18 29±9 0.496 MW
AST: ALT 0.74±0.21 0.82±0.34 0.577 MW
Albumin (g/dL) 4.1±0.27 3.9±0.77 0.732 MW
Bilirubin (total) (mg/dL) 0.44±0.17 0.59±0.38 0.263 MW
White blood cell count(103/uL) 7.6±2.2 6.9±1.6 0.246 MW
Platelet count (103/uL) 274±78 270±69 0.845 2T
Hemoglobin (g/dL) 13±1.1 13±1.7 0.878 2T
Glucose (mg/dL) 116±43 104±32 0.556 MW
Cholesterol (total) (mg/dL) 187±30 190±41 0.808 2T
Triglycerides (mg/dL) 179±144 174±83 0.458 MW
HDL (mg/dL) 47±9 51±11 0.182 2T
CCL-2 (pg/mL) 464±118 486±218 0.902 MW
sFasL (pg/mL) 89±31 82±34 0.516 MW
Portal fibrosis 16 (73%) 10 (67%) 0.976 Chi
Pericellular fibrosis 12 (54%) 0 (0%) n/a

Entries are counts for discrete measures (with percentage of group total given in parentheses) or mean ± S.D. for continuous measures. A p-value of ≤0.05 was considered significant. Significant results are shown in bold text. Chi = chi square test of homogeneity; FE = Fisher’s exact test; MW = Mann-Whitney U test; 2T = two-sample t-test (2-tailed).