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. 2013 Feb 6;8(2):e54812. doi: 10.1371/journal.pone.0054812

Figure 3. Simulation results for a range of shift parameters and number of informative genes.

Figure 3

The true positive rate (TPR, row 1), false discovery rate (FDR, row 2) and false positive rate (FPR, row 3) are reported (y-axis) for shift parameters ranging from 1 to 5.5 (x-axis), when the “true” (under simulation) number of informative genes is equal to 48 (left hand column) or 96 (right hand column). “Informative” genes are assumed to have effects that arise from a normal distribution with mean equal to the shift parameter while all remaining gene-level effects (2960 total) arise from a standard normal distribution. All estimates are based on 500 simulations per condition. *Dots are enlarged to visualize overlapping symbols.