First 6 months after starting antiretroviral therapy
|
Transition probability
|
3 months CD4 0–49 cells/µL |
0,035 (0,029 to 0,044) |
0,040 (0,029 to 0,056) |
3 months CD4 50–199 cells/µL |
0,010 (0,008 to 0,012) |
0,017 (0,013 to 0,022) |
6 months CD4 0–49 cells/µL |
0,011 (0,010 to 0,014) |
0,027 (0,021 to 0,036) |
6 months CD4 50–199 cells/µL |
0,003 (0,003 to 0,004) |
0,011 (0,009 to 0,014) |
First 6 months after restarting antiretroviral therapy
|
Transition probability: 0–6 months |
|
0,008 (0,004 to 0,016) |
0,004 (0,001 to 0,010) |
>6 months on antiretroviral therapy
|
Hazard coefficient due to CD4 and VL
|
CD4 0–49 cells/µL |
VL <1,000 copies/ml |
−5,01 |
−5,03 |
CD4 0–49 cells/µL |
VL 1,000–100,000 copies/ml |
−4,71 |
−4,69 |
CD4 0–49 cells/µL |
VL >100,000 copies/ml |
−3,83 |
−4,13 |
CD4 50–199 cells/µL |
VL <1,000 copies/ml |
−6,00 |
−6,5 |
CD4 50–199 cells/µL |
VL 1,000–100,000 copies/ml |
−5,69 |
−6,16 |
CD4 50–199 cells/µL |
VL <1000 copies/ml |
−4,82 |
−5,6 |
CD4 200–349 cells/µL |
VL >100,000 copies/ml |
−7,25 |
−7,48 |
CD4 200–349 cells/µL |
VL 1,000–100,000 copies/ml |
−6,94 |
−7,14 |
CD4 200–349 cells/µL |
VL <1000 copies/ml |
−6,07 |
−6,58 |
CD4 350–499 cells/µL |
VL >100,000 copies/ml |
−7,63 |
−8,53 |
CD4 350–499 cells/µL |
VL 1,000–100,000 copies/ml |
−7,32 |
−8,19 |
CD4 350–499 cells/µL |
VL >100,000 copies/ml |
−6,45 |
−7,63 |
CD4 ≥500 cells/µL |
VL <1,000 copies/ml |
−7,76 |
−8,16 |
CD4 ≥500 cells/µL |
VL 1,000–100,000 copies/ml |
−7,46 |
−7,82 |
CD4 ≥500 cells/µL |
VL >100,000 copies/ml |
−6,58 |
−7,26 |
Hazard coefficients for Gompertz function
|
alpha |
|
0,93 (0,52 to 1,34) |
1,73 (1,17 to 2,28) |
beta – half-life (months) |
|
20 |
20 |