Table 2. Plasma levels of sTNFR1, sTNFR2, sFAS, sFASL, MMPs, TIMPs and MPO during the first 24 hours after STEMI and reperfusion treatment (n = 46).
| 0 h | 24 h | change (%) | p-value | |
| sTNFR1 (pg/mL) | 1256 (1039, 1481) | 1617 (1216, 1890) | 26 (9.0, 40) | p<0.001 |
| sTNFR2 (pg/mL) | 2170 (1787, 2570) | 2451 (1982, 3269) | 14 (−0.4, 24) | P<0.001 |
| sFAS (pg/mL) | 6527 (5375, 8093) | 7685 (6146, 8655) | 9.9 (−2.7, 27) | P<0.001 |
| sFASL (pg/mL) | 45.3 (35.8, 55.0) | 43.6 (35.7, 51.8) | −5.3 (−12, 2.7) | P = 0.029 |
| MMP-2 (ng/mL) | 196 (172, 222) | 191 (161, 216) | −5 (−14, 4) | P = 0.193 |
| MMP-8 (ng/mL) | 4.0 (2.2, 5.8) | 3.9 (1.8, 6.9) | −6 (−60, 102) | P = 0.808 |
| MMP-9 (ng/mL) | 89 (43, 135) | 62 (31, 153) | −35 (−65, 45) | P = 0.121 |
| TIMP-1 (ng/mL) | 75 (70, 88) | 98 (84, 128) | 29 (16, 52) | P<0.001 |
| TIMP-2 (ng/mL) | 67 (61, 74) | 64 (56, 72) | −4 (−15, 3) | P = 0.024 |
| MPO (ng/mL) | 1245 (260, 1628) | 428 (198, 727) | −65 (−82, −31) | P<0.001 |
Values are given as median (25th, 75th percentile). P-values are shown for Wilcoxon signed ranks test. sTNFR1, soluble tumour necrosis factor receptor 1; sTNFR2, soluble tumour necrosis factor receptor 2; sFAS, soluble FAS; sFASL, soluble FAS ligand; MMP-2, matrix metalloproteinase-2; TIMP, tissue inhibitor of metalloproteinase; MPO, myeloperoxidase; STEMI, ST-elevation myocardial infarction.