Table 1. Subject characteristics.
Colon Cancer (N = 2183) | Rectal Cancer (N = 1948) | |||
No DM | DM | No DM | DM | |
(N = 1895) | (N = 288) | (N = 1719) | (N = 229) | |
Sex (Male/Female) | 1091/804 | 181/107 | 1059/660 | 148/81 |
Age (year±SD) | 59.1±11.6 | 64.0±8.8* | 58.2±11.6 | 62.4±8.8* |
≤50 | 378(19.9) | 18 (6.3) | 391 (22.7) | 13 (5.7) |
51 to ≤60 | 526 (27.8) | 57 (19.8) | 482 (28.0) | 72 (31.4) |
61 to ≤70 | 643 (33.9) | 139 (48.3) | 562 (32.7) | 93 (40.6) |
>70 | 348 (18.4) | 74(25.7) | 284 (16.5) | 51 (22.3) |
BMI (kg/m2 mean±SD) | 23.0±3.1 | 23.6±3.3 | 23.0±3.1 | 23.7±3.2 |
<18.5 | 109 (5.8) | 9 (3.1) | 107 (6.2) | 8 (3.5) |
18.5 to <23 | 766 (40.4) | 101 (35.1) | 704 (41.0) | 78 (34.1) |
23 to <25 | 412 (21.7) | 67 (23.3) | 377 (21.9) | 59 (25.8) |
≥25 | 418 (22.1) | 85 (29.5) | 381 (22.2) | 68 (29.7) |
Missing | 190 (10.0) | 26 (9.0) | 150 (8.7) | 16 (7) |
Family history (Yes %) | 84 (4.4) | 10 (3.5) | 54 (3.1) | 2 (0.9) |
TNM stage | ||||
I | 302 (15.9) | 47 (16.3) | 468 (27.2) | 59(25.8) |
II | 882 (46.5) | 133 (46.2) | 531 (30.9) | 71 (31.0) |
III | 711 (37.5) | 108 (37.5) | 720 (41.9) | 99 (43.2) |
No positive lymph node | ||||
0 | 1182 (62.4) | 180(62.5) | 995 (57.9) | 131 (57.2) |
1 to 4 | 554 (29.2) | 83 (28.9) | 495 (28.8) | 77 (33.6) |
≥5 | 156 (8.2) | 25 (8.7) | 225(13.1) | 21 (9.2) |
Missing | 3 (0.2) | 0 | 4 (0.2) | 0 |
Preoperative CEA | ||||
<5 ng/dl | 1406(74.2) | 186 (64.6) | 1288(74.9) | 148(64.6) |
≥5 ng/dl | 479 (25.3) | 101 (35.1) | 424(24.7) | 81(35.4) |
Missing | 10 (0.5) | 1 (.3) | 7(0.4) | 0 |
Adjuvant therapy | ||||
No | 445 (23.5) | 69 (24.0) | 450 (26.2) | 61 (26.6) |
Chemotherapy alone | 1237 (65.3) | 192 (66.7) | 444 (25.8) | 56 (24.5) |
Radiation alone | 4 (.2) | 0 (0) | 35 (2.0) | 9 (3.9) |
Chemo and radiation | 90 (4.7) | 11 (3.8) | 719 (41.8) | 92 (40.2) |
Missing | 119 (6.3) | 16(5.6) | 71(4.1) | 11 (4.8) |
SD: Standard deviation, Number (%), DM: Diabetes Mellitus, * p<0.05 Significantly different compared with subjects who did not have DM.