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. 2013 Feb 6;8(2):e55196. doi: 10.1371/journal.pone.0055196

Table 1. Subject characteristics.

Colon Cancer (N = 2183) Rectal Cancer (N = 1948)
No DM DM No DM DM
(N = 1895) (N = 288) (N = 1719) (N = 229)
Sex (Male/Female) 1091/804 181/107 1059/660 148/81
Age (year±SD) 59.1±11.6 64.0±8.8* 58.2±11.6 62.4±8.8*
≤50 378(19.9) 18 (6.3) 391 (22.7) 13 (5.7)
51 to ≤60 526 (27.8) 57 (19.8) 482 (28.0) 72 (31.4)
61 to ≤70 643 (33.9) 139 (48.3) 562 (32.7) 93 (40.6)
>70 348 (18.4) 74(25.7) 284 (16.5) 51 (22.3)
BMI (kg/m2 mean±SD) 23.0±3.1 23.6±3.3 23.0±3.1 23.7±3.2
<18.5 109 (5.8) 9 (3.1) 107 (6.2) 8 (3.5)
18.5 to <23 766 (40.4) 101 (35.1) 704 (41.0) 78 (34.1)
23 to <25 412 (21.7) 67 (23.3) 377 (21.9) 59 (25.8)
≥25 418 (22.1) 85 (29.5) 381 (22.2) 68 (29.7)
Missing 190 (10.0) 26 (9.0) 150 (8.7) 16 (7)
Family history (Yes %) 84 (4.4) 10 (3.5) 54 (3.1) 2 (0.9)
TNM stage
I 302 (15.9) 47 (16.3) 468 (27.2) 59(25.8)
II 882 (46.5) 133 (46.2) 531 (30.9) 71 (31.0)
III 711 (37.5) 108 (37.5) 720 (41.9) 99 (43.2)
No positive lymph node
0 1182 (62.4) 180(62.5) 995 (57.9) 131 (57.2)
1 to 4 554 (29.2) 83 (28.9) 495 (28.8) 77 (33.6)
≥5 156 (8.2) 25 (8.7) 225(13.1) 21 (9.2)
Missing 3 (0.2) 0 4 (0.2) 0
Preoperative CEA
<5 ng/dl 1406(74.2) 186 (64.6) 1288(74.9) 148(64.6)
≥5 ng/dl 479 (25.3) 101 (35.1) 424(24.7) 81(35.4)
Missing 10 (0.5) 1 (.3) 7(0.4) 0
Adjuvant therapy
No 445 (23.5) 69 (24.0) 450 (26.2) 61 (26.6)
Chemotherapy alone 1237 (65.3) 192 (66.7) 444 (25.8) 56 (24.5)
Radiation alone 4 (.2) 0 (0) 35 (2.0) 9 (3.9)
Chemo and radiation 90 (4.7) 11 (3.8) 719 (41.8) 92 (40.2)
Missing 119 (6.3) 16(5.6) 71(4.1) 11 (4.8)

SD: Standard deviation, Number (%), DM: Diabetes Mellitus, * p<0.05 Significantly different compared with subjects who did not have DM.