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. Author manuscript; available in PMC: 2013 Feb 7.
Published in final edited form as: Clin Transplant. 2010 Oct 26;25(2):E124–E131. doi: 10.1111/j.1399-0012.2010.01340.x

Table 3.

Association of Adherence with change in eGFR over time*.

Variable Unadjusted
Coefficient ±
for change in
eGFR over
time ± Std
Error
(p-value)		 Adjusted
Coefficient±
for change
in eGFR
over time
Std Error
(p-value)
Interaction between change in eGFR over
time and adherence over 12 months		 −0.24 ± 0.31
(p=0.45)		 −0.20 ± 0.26
(p=0.43)
Time (in months) 0.049 ± 0.27
(p=0.85)		 0.029 ± 0.23
(p=0.90)
Adherence over 6 months 8.48 ± 7.02
(p=0.23)		 −0.73 ± 5.93
(p=0.90)
Constant Term 49.70 ± 6.06
(p<0.001)		 73.39 ± 5.83
(p<0.0001)
Recipient gender: female vs male −4.09 ± 1.43
(p=0.005)
Donor age (per year) −0.44 ± 0.05
(p<0.0001)
Donor Cause of Death (vs Other)
   Cardiovascular
6.93 ± 3.24
(p=0.03)
     Intracranial Hemmorhage 1.22 ± 3.04
(p=0.69)
     Trauma 9.33 ± 2.63
(p=0.0005)
Delayed allograft function −7.02 ± 1.51
(p<0.0001)
*

The interaction term between adherence and change in eGFR describes the association of adherence with change in eGFR over time. The adjusted model was also adjusted for transplant center.

±

Co-efficients were determined using a mixed effects model with the outcome being eGFR. This model also included fixed effects such as date of eGFR measurement in terms of month after transplant, mean adherence over six months and an interaction term between these two variables.