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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Hepatology. 2013 Feb;57(2):577–589. doi: 10.1002/hep.26081

Figure 6. Inflammasome activation is abolished in TLR2−/− mice.

Figure 6

WT and TLR2−/− mice were fed control CSAA (CS) diet, and CDAA (CD) diet for 22 weeks. Closed bars represent WT mice and open bars indicate TLR2−/− mice. (A) Hepatic mRNA expression of NLRP3. Genes were normalized to 18S RNA as an internal control. (B) FFA concentrations in the portal vein. (C) Caspase-1 activation in the liver. (D) Serum IL-1β concentrations. (E) Serum IL-1α concentrations. N.D; not detected. Data represent mean ±SD, *p<0.05. n.s.; not significant.