Table 5.
Migraine with Aura (MA) in EPGP Participants
| No. participants | Unadjusted | Adjusted | ||||
|---|---|---|---|---|---|---|
| Total | With MA (%) |
OR* | (95% CI) | OR** | (95% CI) | |
| All participants | 730 | 82 (11.2) | -- | -- | -- | -- |
| Female | 445 | 66 (14.8) | 2.9 | (1.67–5.13) | 2.7 | (1.51–4.76) |
| Male | 285 | 16 (5.6) | 1.0 | (referent) | 1.0 | (referent) |
| Age (years) | ||||||
| 12–24 | 340 | 22 (6.5) | 1.0 | (referent) | 1.0 | (referent) |
| 25–39 | 189 | 27 (14.3) | 2.4 | (1.31–4.43) | 2.1 | (1.07–3.98) |
| ≥40 | 201 | 33 (16.4) | 2.8 | (1.63–4.93) | 2.2 | (1.15–4.22) |
| Probands | 371 | 34 (9.2) | 1.0 | (referent) | 1.0 | (referent) |
| Siblings | 231 | 27 (11.7) | 1.3 | (0.83–2.08) | 1.2 | (0.74–2.11) |
| Parents | 128 | 21 (16.4) | 1.9 | (1.10–3.43) | 1.1 | (0.57–2.14) |
| Generalized epilepsy | 435 | 44 (10.1) | 1.0 | (referent) | 1.0 | (referent) |
| Focal epilepsy | 295 | 38 (12.9) | 1.3 | (0.83–2.08) | 1.3 | (0.77–2.04) |
| No. additional first-degree relatives with seizure disorders | ||||||
| None | 549 | 55 (10.0) | 1.0 | (referent) | 1.0 | (referent) |
| 1 | 133 | 15 (11.3) | 1.1 | (0.60–2.16) | 1.1 | (0.55–2.09) |
| ≥2 | 48 | 12 (25.0) | 3.0 | (1.42–6.32) | 2.5 | (1.13–5.46) |
*
Bivariate odds ratio and 95% confidence interval, computed by generalized estimating equations.
**
Multivariate odds ratio and 95% confidence interval, computed by generalized estimating equations with all variables in table included in the model.