Table 3.

PFA-100 Collagen-Epinephrine closure time of group O donor platelet depleted samples mixed at a ratio of 4:1 with either group O or group A platelets.

	Group O Whole Blood (Mean + SD)^{^} (N = 8)
	PLT Count (×10³/μL)	Hct (%)	Epinephrine-CT (Seconds) [% Prolongation]

Baseline	250 ± 93	36 ± 3.1	161 ± 41

After PLT Depletion	45 ± 45	46 ± 13.3	-
After PLT Depletion	p < 0.001	p = 0.071	-

After 60 min incubation at 37°C with O PLT	172 ± 94	37 ± 1.2	183 ± 53
After 60 min incubation at 37°C with O PLT	p = 0.120	p = 0.437	p = 0.393 [14%]

After 60 min incubation at 37°C with A PLT	109 ± 63^*	34 ± 4.8	240 ± 68^#
After 60 min incubation at 37°C with A PLT	p = 0.004	p = 0.443	p = 0.016 [49%]

PLT, platelet; Hct, hematocrit; Epinephrine-CT, collagen-epinephrine closure time.

^{^}

p value in comparison to the baseline results.

Platelet agglutination and falsely increased WBC (due to platelet agglutination) were reported on the cell counter.

Epinephrine-CT of three samples exposed to A platelets were > 300 seconds; however, for statistical purposes, Epinephrine-CT of these samples were considered 300 seconds.