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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Transfusion. 2012 May 25;53(2):382–393. doi: 10.1111/j.1537-2995.2012.03718.x

Table 5.

Thrombin generation parameters of group A and group O platelets. Samples were mixed with autologous plasma and O plasma with an anti-A titer of 1:1024 for both groups; O plasma with low anti-A titers (range of 1:8–1:64) and B plasma in group A samples; and A plasma in group O samples.

Group A PLT (N = 11)^ Group O PLT (N = 6)^
Autologous Plasma O Plasma (anti-A range of 1:8–1:64) B Plasma O Plasma (Anti-A 1:1024) Autologous Plasma O Plasma (Anti-A 1:1024) A Plasma
Lag time (min) 8.2 ± 0.6 8.4 ± 0.9 6.5 ± 0.7* 6.4 ± 1.4* 6.4 ± 0.8 5.9 ± 0.5 6.6 ± 1.2
Time to Peak (min) 17.6 ± 0.7 16.8 ± 1.3 15.2 ± 1.5* 15.7 ± 2.3* 12.8 ± 3.4 13 ± 2.4 13.2 ± 3
Peak (nM) 139 ± 25 144 ± 31 159 ± 37 107 ± 14* 145 ± 37 132 ± 47.5 135 ± 45
ETP (nM* min) 2006 ± 218 1678 ± 731 1910 ± 720 1614 ± 212* 1589 ± 195 1547 ± 232 1544 ± 176
Velocity Index (nM/min) 14.9 ± 3.3 17.2 ± 3.6 18.6 ± 5.1 11.6 ± 1.8* 26.6 ± 15.2 22.8 ± 18.6 23.8 ± 15.4

PLT, platelet; ETP, Endogenous thrombin potential (the area under the thrombin concentration versus time curve).

^

Data are presented as mean ± standard deviation.

*

Values are statistically significant (p < 0.05) in comparison to the autologous plasma values.