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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Blood Cells Mol Dis. 2012 Dec 21;50(3):171–176. doi: 10.1016/j.bcmd.2012.11.007

Figure 3.

Figure 3

CD41+ expression (A) and Mk ploidy (B) of bone marrow mononuclear cells harvested from NIC-treated and control mice. (i) Mice treated 3 times per week with saline (open bar), 250 mg/kg (light gray bar) or 1000 mg/kg NIC (gray bar) were sacrificed on day 56 in the first experiment. Bone marrow was isolated from femurs and evaluated individually for each mouse. Data represents the mean ± SEM for n = 3, 5, or 6 mice for the saline control, 250 mg/kg NIC, and 1000 mg/kg NIC conditions respectively. (ii) Mice treated 3 times per week with saline (open bar) or 1000 mg/kg NIC (gray bar) were sacrificed on day 14 or 28 in the second experiment. Bone marrow from individual mice was isolated from femurs and evaluated individually for each mouse. Data represents the mean ± SEM for n = 1 or 2 for saline and NIC conditions, respectively, on day 14 and n = 4 on day 28. (iii) Mice treated daily with saline (open bar) or 1000 mg/kg NIC (gray bar) were sacrificed on day 28 in the third experiment. Bone marrow from femurs of 2 mice was pooled together for analysis.