Figure 2.

Physiological characterization of rVSV-infected and uninfected layer 5 cortical pyramidal neurons following injection of rVSV(RABV-G) into the CP. Slices were cut 12 hpi and recordings were taken over the subsequent 6 h. (A) Example spike trains driven by 100, 200, and 400 pA square current pulses lasting 1 s for infected (left) and uninfected (right) neurons. (B) A summary plot showing current/action potential firing frequency relationships are unaffected by infection (infected cells, N = 7; uninfected cells, N = 6). Horizontal bars denote averages. Infection does not alter the (C) input resistance, the (D) capacitance, or (E) resting membrane voltages (infected cells, N = 10, uninfected cells, N = 9). Horizontal bars denote mean with standard error of the mean.