Sorcin inhibits glucose-induced caspase activation. A: Western blot showing protein levels of caspase-9, caspase-3, cleaved caspase-3, poly(ADP-ribose)polymerase (PARP), and cleaved PARP in cells exposed to normal glucose (NG, 5.5 mM glucose + 20 mM mannitol), high glucose (HG, 25 mM), and HG + Adv-sorcin (HG + Sor). B: averages of densitometry values of each sample. Values are means ± SE, n = 4 for each group. *P < 0.05 vs. NG. &P < 0.5 vs. HG.