Table 1.
Parameter | Larson et al. (18) |
Pan et al. (16) |
Bieling et al. (17) |
---|---|---|---|
Fast motor | |||
Wild kinesin-I |
OSM-3 |
Xklp1 |
|
Slow motor | |||
Mutant kinesin-1 | Kinesin-II | Xkid | |
Binding rate, fast π0f | 5/s (32) | 5/s (32) | 5/s (32) |
Binding rate, slow π0s | 5/s (18,32) | 5/s (32) | 5/s (32) |
Unbinding rate, fast ϵ0f | 1/s (33,34) | 1/s (33,34) | 1/s (33,34) |
Unbinding rate, slow ϵ0s | 1/s (18,33,34) | 1/s (33,34) | 1/s (33,34) |
Detachment force, fast Fdf | 3 pN (34) | 6 pN (this work) | 6 pN (this work) |
Detachment force ratio η ≡ Fds/Fdf | 0.45(23) | 3.3 (this work) | 1.9 (this work) |
Stall force, fast Fsf | 6 pN (34) | 6 pN (34) | 6 pN (34) |
Stall force, slow Fss | 6 pN (18,34) | 6 pN (34) | 6 pN (34) |
Zero load velocity, fast vf | 0.522 μm/s (18) | 1.09 μm/s (16) | 1.0 μm/s (17) |
Zero load velocity, slow vs | 0.034 μm/s (18) | 0.34 μm/s (16) | 0.1 μm/s (17) |
5 | 5 | 5 | |
2 | 1 | 1 | |
0.065 | 0.31 | 0.1 |