Skip to main content
. 2013 Feb 5;104(3):705–715. doi: 10.1016/j.bpj.2012.12.003

Table 1.

Comparison of ΔSASA and relative binding ΔG for complexes between titin & CaM2, neck & CaM2, and ABD & neck-CaM2

Receptor Receptor SASA (A2) Ligand Ligand SASA (A2) Complex SASA (A2) ΔSASA (A2) ΔG (kcal mol−1)a
CaM2b 5010 Titin 2597 6281 1326 −23.3
CaM2 4598 Neck 2498 5760 1318 −19.7
neck-CaM2 5760 ABD 11578 15,298 2040 −24.7
a

Binding free energies were estimated using FastContact (36).

b

For the titin-CaM2 complex, all values are averages over the 30 NMR structures in PDB 1H8B (23).