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. Author manuscript; available in PMC: 2013 Feb 7.
Published in final edited form as: Neuropharmacology. 2010 Dec 8;60(4):626–632. doi: 10.1016/j.neuropharm.2010.11.026

Fig. 5. Effect of gabapentin on mechanical sensitization after chronic constriction injury.

Fig. 5

(A) PWTs (g, mean ± SEM) in response to von Frey filament stimulation were monitored before and 7 days after CCI surgery. On day 7, gabapentin (3 [▼, ▽], 10 [◆, ◇] or 30 [■, □] mg / kg body weight) or vehicle (●, ○) were injected i.p. and PWTs were monitored for 3 hours after gabapentin injection. n = 6 mice per group. (B) Percent maximum possible effect of gabapentin (○, solid line) on mechanical sensitization after CCI. For comparison the data for HZ166 (●, dotted line) are displayed (same as in Fig. 2B).