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. 2012 Dec 12;304(4):F440–F450. doi: 10.1152/ajprenal.00487.2011

Fig. 5.

Fig. 5.

More kidney neutrophil infiltration in CHOP−/− mice after LPS treatment. A: neutrophils (arrows) in glomeruli of WT mice treated with LPS (×20 magnification, ×40 inset). B: neutrophils (arrows) in glomeuli of CHOP−/− mice treated with LPS (×20 magnification, ×40 inset). C: neutrophil (arrow) in kidney interstitium of WT mice treated with LPS (×40 magnification). D: neutrophils (arrows) in kidney interstitium of CHOP−/− mice treated with LPS (×40 magnification). E: quantification of naphthol AS-D-positive cells in kidney glomeruli. Although LPS treatment induced infiltration of neutrophils in both WT and CHOP−/− mice, CHOP−/− mice had 3.5-fold higher number of infiltrating neutrophils compared with WT mice after LPS treatment (**P < 0.01). F: quantification of naphthol AS-D-positive cells in kidney interstitium. CHOP−/− mice had 3.5-fold higher number of infiltrating neutrophils compared with WT mice after LPS treatment (**P < 0.01). Data are expressed as means ± SD.