Fig. 8.

IκB protein levels are reduced in CHOP ^−/− mice after LPS treatment. Proteins were isolated from LPS-treated CHOP^−/− and WT mice kidneys. Representative Western blot (A) and densitometric analysis (B) showing significant reduction in IκB levels in CHOP^−/− mice kidneys after LPS injection (*P < 0.05). Representative Western blot (C and E) and densitometric analysis (D and F) showing no significant differences in phosphorylated P38 and phosphorylated JNK levels in CHOP^−/− and WT mice kidneys after LPS injection. Data are expressed as means ± SD.