Table 1.
Parameter values
| PNa, 10−5 cm/s | Purea, 10−5 cm/s | Diffusivity, 10−5 cm2/s | |
|---|---|---|---|
| DTL+ | 0 | 13 | |
| DTL− | 0 | 180 | |
| ATL | 80 | 190 | |
| CD | 1 | 35 | |
| DVR | 76 | 360 | |
| AVR | 750 | 690 | |
| Na | 0.3 | ||
| Urea | 0.276 |
Values from Refs. 13 and 16. For effective permeability (Peff) calculations, diffusivity values are reduced by fivefold (from the correct values of 1.5 for Na and 1.38 for urea) due to interstitial viscosity (15). PNa, Na permeability; Purea, urea permeability; DTL+, AQP1-positive descending thin limbs (DTL); DTL−, AQP1-negative DTL; ATL, ascending thin limb; CD, collecting duct; DVR, descending vasa recta; AVR, ascending vasa recta.