Fig. 6.

Occurrence and characterization of Ca²⁺ sparks induced by soluble integrin antibody. XT line scan image of a single VSMC exhibiting Ca²⁺ sparks (white arrowheads) in the presence of β₁-integrin antibody (A). The whole image is composed of 512 scan lines collected at 500 Hz. Distribution of full width at half the maximum (FWHM, amplitude) and full duration at half maximum (FDHM, duration) of Ca²⁺ sparks in the presence of α₅-integrin antibody (B and C, 83 Ca²⁺ sparks), β₁-integrin antibody (D and E, 71 Ca²⁺ sparks), and β₂-integrin antibody (F and G, 33 Ca²⁺ sparks) were similar. Medians of FWHM are 0.9, 1.2, and 0.8 μm, respectively. Corresponding medians FDHM are 20, 22, and 18 μs.