Skip to main content
. 2013 Feb 7;3:1225. doi: 10.1038/srep01225

Figure 5. Identified hydrogen bond interaction paths from the site of mutation to His114 in ANG mutants.

Figure 5

Observed hydrogen bond interaction paths from the site of mutation to catalytic residue His114 are presented for I46V, K17E, R31K, D22G, N49S and T80S angiogenin mutants. The node represents the amino acid residue linked through hydrogen bond and edge represents the bond length between them. Simulation results show that these hydrogen bond interaction paths are conserved and hence induces loss of ribonucleolytic activity in ANG mutants.