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. 1973 Sep;12(3):548–555. doi: 10.1128/jvi.12.3.548-555.1973

RNA-Dependent DNA Polymerase Activity in Preparations of a Mutant of Newcastle Disease Virus Arising from Persistently Infected L Cells

Phillip A Furman 1, Jules V Hallum 1
PMCID: PMC356661  PMID: 4127031

Abstract

RNA-dependent DNA polymerase activity was found in peparations of a mutant of Newcastle disease virus. The enzyme activity was not found in wild-type virus preparations.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baltimore D. RNA-dependent DNA polymerase in virions of RNA tumour viruses. Nature. 1970 Jun 27;226(5252):1209–1211. doi: 10.1038/2261209a0. [DOI] [PubMed] [Google Scholar]
  2. Baltimore D., Smoler D. Primer requirement and template specificity of the DNA polymerase of RNA tumor viruses. Proc Natl Acad Sci U S A. 1971 Jul;68(7):1507–1511. doi: 10.1073/pnas.68.7.1507. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Blair C. D., Duesberg P. H. Myxovirus ribonucleic acids. Annu Rev Microbiol. 1970;24:539–574. doi: 10.1146/annurev.mi.24.100170.002543. [DOI] [PubMed] [Google Scholar]
  4. Duesberg P. H., Robinson W. S. Isolation of the nucleic acid of Newcastle disease virus (NDV). Proc Natl Acad Sci U S A. 1965 Sep;54(3):794–800. doi: 10.1073/pnas.54.3.794. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Faras A. J., Erikson R. L. L-cell virion ribonucleic acid. J Virol. 1969 Jul;4(1):31–35. doi: 10.1128/jvi.4.1.31-35.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Gallo R. C. RNA-dependent DNA polymerase in viruses and cells: views on the current state. Blood. 1972 Jan;39(1):117–137. [PubMed] [Google Scholar]
  7. Gilden R. V., Oroszlan S. Group-specific antigens of RNA tumor viruses as markers for subinfectious expression of the RNA virus genome. Proc Natl Acad Sci U S A. 1972 Apr;69(4):1021–1025. doi: 10.1073/pnas.69.4.1021. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Hallum J. V., Thacore H. R., Youngner J. S. Effect of exogenous interferon on L cells persistently infected with Newcastle disease virus. Infect Immun. 1972 Jan;5(1):145–146. doi: 10.1128/iai.5.1.145-146.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Hallum J. V., Thacore H. R., Youngner J. S. Factors affecting the sensitivity of different viruses to interferon. J Virol. 1970 Aug;6(2):156–162. doi: 10.1128/jvi.6.2.156-162.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Huang A. S., Baltimore D., Bratt M. A. Ribonucleic acid polymerase in virions of Newcastle disease virus: comparison with the vesicular stomatitis virus polymerase. J Virol. 1971 Mar;7(3):389–394. doi: 10.1128/jvi.7.3.389-394.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  12. Lin F. H., Thormar H. Ribonucleic acid-dependent deoxyribonucleic acid polymerase in visna virus. J Virol. 1970 Nov;6(5):702–704. doi: 10.1128/jvi.6.5.702-704.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Oroszlan S., Bova D., Martin White M. H., Toni R., Foreman C., Gilden R. V. Purification and immunological characterization of the major internal protein of the RD-114 virus. Proc Natl Acad Sci U S A. 1972 May;69(5):1211–1215. doi: 10.1073/pnas.69.5.1211. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Schlom J., Harter D. H., Burny A., Spiegelman S. DNA polymerase activities in varions of visna virus, a causative agent of a "slow" neurological disease. Proc Natl Acad Sci U S A. 1971 Jan;68(1):182–186. doi: 10.1073/pnas.68.1.182. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Spiegelman S., Burny A., Das M. R., Keydar J., Schlom J., Travnicek M., Watson K. Characterization of the products of DNA-directed DNA polymerases in oncogenic RNA viruses. Nature. 1970 Aug 8;227(5258):563–567. doi: 10.1038/227563a0. [DOI] [PubMed] [Google Scholar]
  16. Temin H. M., Mizutani S. RNA-dependent DNA polymerase in virions of Rous sarcoma virus. Nature. 1970 Jun 27;226(5252):1211–1213. doi: 10.1038/2261211a0. [DOI] [PubMed] [Google Scholar]
  17. Thacore H., Youngner J. S. Cells persistently infected with Newcastle disease virus. II. Ribonucleic acid and protein synthesis in cells infected with mutants isolated from persistently infected L cells. J Virol. 1970 Jul;6(1):42–48. doi: 10.1128/jvi.6.1.42-48.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Thacore H., Youngner J. S. Cells persistently infected with newcastle disease virus: I. Properties of mutants isolated from persistently infected L cells. J Virol. 1969 Sep;4(3):244–251. doi: 10.1128/jvi.4.3.244-251.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]

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