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TGR5 expression. A: low-power view (×40) shows that TGR5 expression was increased in the intestinal metaplasia (left) when compared with normal gastric mucosa (right). B: high-power view (×400) shows that the TGR5 staining pattern is membranous and cytoplasmic. C: strong and diffuse TGR5 immunohistochemical staining in intestinal-type gastric adenocarcinoma. D: focal TGR5 immunohistochemical staining in diffuse-type gastric adenocarcinoma. Original magnifications ×100.
