Table 3.
Response in each study depending on number of induction cycles
| 1 Cycle | 2 Cycles | All | |||||
|---|---|---|---|---|---|---|---|
| No CR | CR | No CR | CR | No CR | CR | ||
| N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | p-value* | |
| E3483 | 57 (23) | 189 (77) | 111 (46) | 128 (54) | 168 (35) | 317 (65) | <0.001 |
| PC486 | 13 (28) | 33 (72) | 16 (24) | 51 (76) | 29 (26) | 84 (74) | 0.66 |
| E3489 | 218 (33) | 453 (68) | 2 (3) | 75 (97) | 220(29) | 528 (71) | <0.001 |
| E1490 | 20 (27) | 55 (73) | 24 (67) | 12 (33) | 44 (40) | 67 (60) | <0.001 |
| E2491 | 29 (25) | 87 (75) | 20 (34) | 39 (66) | 49 (28) | 126 (72) | 0.22 |
| E3993 | 141 (52) | 128 (48) | 57 (72) | 22 (28) | 198(57) | 150 (43) | 0.002 |
| All | 478 (34) | 945 (66) | 230 (41) | 327 (59) | 708(36) | 1272(64) | 0.001 |
*
: p-value for comparison of CR rates between 1 and 2 cycles