Table 3. Lung weight and number ofC. trachomatis MoPn IFU recovered from the lungs following the i.n. challenge.
Vaccine | Lung weight (gr.; mean ± SE) | No. IFU lung culture Median (range) × (106) |
---|---|---|
nMOMP + CTB-CpG | 0.30 ± 0.01 a, b | 1.63 (0.67-21.06)d,e |
nMOMP + CT + CpG ODN | 0.27 ± 0.03c | 1.32 (0.02-11.77)f |
Ovalbumin + CTB-CpG | 0.33 ± 0.01 | 55.45 (1.30-181.72) |
Ovalbumin + CT + CpG ODN | 0.35 ± 0.01 | 55.34 (15.07-192.05) |
C. trachomatis | 0.22 ± 0.01 | <0.00005 |
p > 0.05 as determined by the Student t test for the comparison with the group immunized with nMOMP + CT + CpG ODN
p < 0.05 as determined by the Student t test for the comparison with the group immunized with ovalbumin + CTB-CpG
p < 0.05 as determined by the Student t test for the comparison with the group immunized with ovalbumin + CT + CpG ODN
p > 0.05 as determined by the Mann Whitney U-test for the comparison with the group immunized with nMOMP + CT + CpG ODN
p < 0.05 as determined by the Mann Whitney U-test for the comparison with the group immunized with ovalbumin + CTB-CpG
p < 0.05 as determined by the Mann Whitney U-test for the comparison with the group immunized with ovalbumin + CT + CpG ODN