0.8–1.4×108 bacteria of the two different strains of S. xylosus (720 and 1056 B) and the S. aureus 1056A isolated from infected paws of Ncf1 mutant mice were injected i.v. into Ncf1 mutant (Ncf1*/*) mice (N=10 for S. aureus and S. xylosus 720 and N=5 for S. xylosus 1056 A) and into wt (Ncf1+/+) mice (N=10). Mean and SEM is shown.
Weight loss (A, C and E) and survival (B, D, and F) were measured up to 7 days after bacterial challenge. Survival curves were displayed by Kaplan-Meier and intergroup comparisons assessed by the log-rank method. * P<0.05, ** P<0.01