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. 2013 Jan 15;3(1):e212. doi: 10.1038/tp.2012.136

Figure 4.

Figure 4

The adenosine receptor agonist 2-chloro-N(6)-cyclopentyladenosine(CCPA) alters network patterns of electrical activity and sleep architecture. (a) The percent time awake is decreased during CCPA administration (arrows). (b) Normalized power spectrum at ZT=12 during wakefulness at hours 12, 36, 84, and 108 after initial drug administration. Data are normalized to the total power of the EEG between 0.5 and 40 Hz. (c) Normalized power spectrum from 0.5 to 4.0 Hz for wake states at 12, 36, 84, and 108 h after initial drug administration. (d) Normalized power during wake of the delta (.5–4 Hz), theta (5–8 Hz) alpha (9–13 Hz), and gamma (20–40 Hz). *P⩽0.05, **P⩽0.01, ***P⩽0.001.