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Ephrin-A5 is expressed extensively within the developing eye. A-E: EphA5-AP staining shows significant expression of ephrin-A ligand in the wild-type eye as early as E12 and persists through postnatal ages. Scale bars are in micrometers. F-J: Little to no EphA5-AP staining is observed in the ephrin-A5-/- eye indicating that ephrin-A5 is the major ephrin-A ligand expressed in the eye. Scale bars are in micrometers.
