Table 2.

The levels of cytokines in culture supernatants of IDC and DC in MS patients

Cytokines(pg/ml ∘ U/ml	Treated patients
	IDC		IDC-LPS
	Man	Women	Man	Women
IL10	5.3 ± 0.1a	3.3 ± 0.9	73.9 ± 37.5	41.2 ± 7.9
IL12p70	0 ± 0.02	0.13 ± 0.13b	3.3 ± 3.1	4.5 ± 1.3i
IL12p40	58.2 ± 11.4	35.8 ± 5.9d	3834 ± 796l	3863 ± 260m
TGFβ	22156 ± 1091e	21792 ± 701f	20701 ± 1103n	20164 ± 633p
∘sCD30	7.01 ± 0.4g	6.9 ± 1.1h	13.5 ± 1.1q	14.7 ± 1.1r
Cytokines(pg/ml ∘ U/ml	Untreated patients
	IDC		IDC-LPS
	Man	Women	Man	Women
IL10	0.6 ± 0.6a	1.1 ± 0.5	27.5 ± 19.2	55.8 ± 13.1
IL12p70	0.37 ± 0.9c	2.9 ± 0.6b,c	9.7q ± 6.5	17.1 ± 3.8i
IL12p40	51.9 ± 6.8	63.7 ± 7.3d	5999 ± 277l	5094 ± 647m
TGFβ	16582 ± 813e	16400 ± 575f	14726 ± 642n	14210 ± 601p
∘sCD30	27.2 ± 24g	26.8 ± 5h	36.9 ± 3.2q	38.1 ± 3.5r

Cytokine levels were determined in culture supernatants of IDC (to evaluate the APC influence on immune response in resting conditions) and of DC (to evaluate the APC influence on immune response in activation conditions). The levels are expressed as mean (or median) ± standard error, as appropriate. Statistical differences between groups were determined using the Mann–Whitney U-test or Student’s t-test as appropriate: aa p = 0.008; bb p < 0.0001; cc p = 0.03; dd p = 0.006; ee p = 0.004; ff p < 0.0001; gg p = 0.0007; hh p < 0.0001; ii p = 0.001; ll p = 0.013; mm p = 0.006; nn p = 0.001; pp p = 0.001; qq p = 0.001; rr p = 0.001.