Table 1.
Baseline characteristics of the risk factors used in the Rotterdam Ischemic Heart Disease and Stroke Computer Simulation (RISC) model for the 3,478 Rotterdam study participants and 25,492 European Prospective Investigation of Cancer (EPIC)-Norfolk study participants
| Variable | RISC (n = 3,478) | EPIC (n = 25,492) |
|---|---|---|
| Age | 69.0 (62 to 75) | 59.2 (51 to 67) |
| Male subjects, % | 39% | 45% |
| Smoker | ||
| Never | 34.5% | 46.0% |
| Former | 41.9% | 42.3% |
| Current | 23.6% | 11.7% |
| BMI | 26.3 (23.8 to 28.5) | 26.3 (23.7 to 28.4) |
| WHR | 0.91 (0.84 to 0.97) | 0.86 (0.78 to 0.93) |
| Systolic BP | 140.0 (124 to 155) | 135.5 (122.5 to 146.5) |
| Diastolic BP | 74.1 (66 to 82) | 82.5 (74.5 to 89.5) |
| Hypertension | 36.4% | 29.9% |
| Total cholesterol | 6.67 (5.8 to 7.4) | 6.19 (5.4 to 6.9) |
| HDL cholesterol | 1.34 (1.1 to 1.5) | 1.41 (1.1 to 1.6) |
| Glucoseb | 6.93 (5.5 to 7.5) | 6.67 (5.5 to 7.3) |
| Creatinine | 82.5 (72 to 91) | 86.7 (76 to 97) |
| Diabetes mellitus | 10.7% | 12.2% |
| Angina pectorisb | 10.4% | 9.2% |
| Atrial fibrillationb | 2.5% | 2.9% |
| Intermittent claudicationb | 2.1% | 1.5% |
| TIAb | 5.1% | 4.8% |
| CVD | 17.8% | 4.3% |
| Family history of MI | 16.3% | 18.4% |
| Family history of CVD | 23.0% | 23.3% |
Abbreviations: BMI, body mass index; BP, blood pressure; CVD, cardiovascular disease; MI, myocardial infarction; TIA, transient ischemic attack; WHR, waist-to-hip ratio.
aAverage values and inter-quartile ranges (brackets) are given for continuous variables, while categorical variables are given as percentages.
bIndicates imputed risk factors for the EPIC-Norfolk dataset.