Table 4. Concentration of intracellular glucose-6-phosphate and fructose-6-phosphate in hypoxic non-replicating M. tuberculosis strains.
Glucose in medium | Glucose-6-phosphate (µmol crude protein g−1) | Fructose-6-phosphate (µmol crude protein g−1) | ||
Day 6 | Day 20 | Day 6 | Day 20 | |
+ | 38.2/40.5 | 126.8/150.1 | 4.5/3.8 | 3.2/3.9 |
− | 29.8/27.7 | 41.4/55.3 | 2.1/3.3 | 1.5/1.9 |
Concentration of intracellular metabolites of wild-type M. tuberculosis in Wayne model of hypoxia at different time points. Each biological sample was measured in duplicate. The data represent the values obtained for each duplicate of each biological sample. This experiment was repeated as least once independently and comparable values and trends were observed.