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. 2013 Feb 7;8(2):e53103. doi: 10.1371/journal.pone.0053103

Figure 5. Blockade of monocyte binding to endothelial cells by APC in different concentrations under flow conditions.

Figure 5

Monocyte binding to HUVECs in dynamic adhesion assays after 5 min (left) and 10 min venous flow (middle), and after 1 min arterial flow (right). Pre-treatment of HUVECs with 10 µg/mL activated protein C (drotrecogin alfa) (dark grey bars) diminished monocyte adhesion compared to 1 µg/mL (light grey bars) and 5 µg/mL (grey bars) drotrecogin alfa. (## p<0.005; # p<0.05 vs. 1 µg/mL APC).