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. 2013 Feb 7;8(2):e53103. doi: 10.1371/journal.pone.0053103

Figure 6. Equal blocking of monocyte binding to endothelial cells by anti-EPCR and APC under flow conditions.

Figure 6

Monocyte binding to HUVECs in dynamic adhesion assay after 5 min (left) and 10 min venous flow (middle), and after 1 min arterial flow (right). Pre-treatment of HUVECs with anti-EPCR (dark grey bars), anti-Mac-1 (light grey bars), or with activated protein C (drotrecogin alfa; crosshatched bars) diminished monocyte adhesion to an equal extent compared to control. (*** p<0.0001; ### p<0.0005; ## p<0.005; # p<0.05 vs. no blocking; ns  =  statistically not signifiant).