Table 5. GSEA pathways down-regulated due to treatment with FO diet, as compared to control samples.

Pathway	NominalP-value*	FDRq value	Pathway (continued)	NominalP-value	FDRq value
Organelle inner membrane	0.0000	0.0185	Cellular lipid catabolic process	0.0088	0.0519
Microbody	0.0000	0.0179	Mitochondrial membrane	0.0100	0.0163
Peroxisome	0.0000	0.0161	Cofactor metabolic process	0.0101	0.0600
Transferase activity – transferring acyl groups	0.0000	0.0172	Hsa00620: Pyruvate metabolism	0.0105	0.0581
Transferase activity – transferring groups other thanamino acyl groups	0.0000	0.0214	Detection of stimulus involved in sensory perception	0.0122	0.0668
Mitochondrial envelope	0.0020	0.0142	Oxidoreductase activity	0.0123	0.0616
Mitochondrion	0.0021	0.0132	Energy derivation by oxidation of organic compounds	0.0125	0.0533
Hsa00020: Citrate cycle	0.0021	0.0433	Hsa00071: Fatty acid metabolism	0.0126	0.0468
Electron carrier activity	0.0040	0.0173	Lipid catabolic process	0.0128	0.0592
Coenzyme metabolic process	0.0041	0.0508	Mitochondrial respiratory chain	0.0166	0.0221
Mitochondrial inner membrane	0.0041	0.0182	Aerobic respiration	0.0189	0.0585
Cellular respiration	0.0042	0.0435	Hsa00030: Pentose phosphate pathway	0.0199	0.0725
Envelope	0.0058	0.0584	Mitochondrion organization and biogenesis	0.0218	0.0795
Organelle envelope	0.0058	0.0563	Mitochondrial lumen	0.0219	0.0469
Mitochondrial part	0.0059	0.0175	Mitochondrial matrix	0.0219	0.0445
Mitochondrial membrane part	0.0060	0.0117	Nucleobase – nucleoside and nucleotide metabolic process	0.0246	0.0811
Generation of precursor metabolites and energy	0.0060	0.0559	Cofactor biosynthetic process	0.0288	0.0932
Hsa00190: Oxidative phosphorylation	0.0061	0.0214	Oxidoreductase activity – acting on CH-OH group of donors	0.0288	0.0734
Fatty acid metabolic process	0.0064	0.0378	Hsa00650: Butanoate metabolism	0.0295	0.0919
Hsa00640: Propanoate metabolism	0.0084	0.0499	Hsa00280: Valine, leucine, and isoleucine degradation	0.0343	0.0602

^* P<0.05;

FDR q<0.1.