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In vitro VN assay was performed with HuMAbs 5A7 (red), 3A2 (blue),10C4 (green) and control IgG (D23-1B3B9; black). HuMAbs (100 µg/ml) were serially four-fold diluted. The percentage of neutralization was estimated as the viral infectivity under HuMAb-treated conditions compared with that without HuMAb. Upper panels are Yamagata lineage viruses and lower panels are Victoria lineage viruses.
