Table 2.
Data from the Participants Enrolled in the MAGIC Study
| Variable |
Cases (n = 1,304) |
Controls (n = 1,334) |
p Value | |||
|---|---|---|---|---|---|---|
| n | % | n | % | |||
| Age (years) | 51.7 ± 13.8 | 51.3 ± 14.2 | 0.468 | |||
| Sex | male | 638 | 48.9% | 649 | 48.7% | 0.887 |
| female | 666 | 51.1% | 685 | 51.3% | ||
| Smoking | yes | 271 | 20.8% | 240 | 18.0% | 0.070 |
| no | 1,033 | 79.2% | 1,094 | 82.0% | ||
| Malignancy | yes | 81 | 6.2% | 6 | 0.4% | 1.179 × 10−16 |
| no | 1,223 | 93.8% | 1,328 | 99.6% | ||
| Immobility | yes | 30 | 2.3% | 15 | 1.2% | 0.038 |
| no | 1,274 | 97.7% | 1,319 | 98.8% | ||
| Pregnancy or puerperium | yes | 34 | 2.6% | 18 | 1.3% | 0.020 |
| no | 1,270 | 97.4% | 1,316 | 98.7% | ||
| OCT or HRP | yes | 16 | 1.2% | 7 | 0.5% | 0.052 |
| no | 1,288 | 98.8% | 1,327 | 99.5% | ||
| Lupus anticoagulant | positive | 65 | 5.0% | 12 | 0.9% | 4.61 × 10−10 |
| negative | 1,239 | 95.0% | 1,322 | 99.1% | ||
Years of age are expressed as means ± SD. The age of cases is the age at the first incident, and the age of controls is the age at enrollment. Age was further divided into three levels: under 40 years, 40–60 years, and over 60 years. Immobility and OCT reflect the 4 weeks prior to the VT incident. The following abbreviations are used: VT, venous thrombosis; OCT, oral contraceptives; and HRT, hormone-replacement therapy.