Table 1.
RhoA GEFs and GAPs which associate with the cytoskeleton or adhesions.
| GEFs | localization | references |
|---|---|---|
| p115 (ArhGEF1) | Cell-ECM adhesion | (33, 108) |
|
| ||
| GEF-H1 (ArhGEF2) | Cell-ECM adhesion | (33, 34) |
| Cell-Cell adhesion | (41, 42) | |
| microtubule | (145) | |
|
| ||
| LARG (ArhGEF12) | Cell-ECM adhesion | (33, 108) |
|
| ||
| Vav | Cell-ECM adhesion | (146) |
|
| ||
| p190RhoGEF | Cell-ECM adhesion | (109) |
| microtubule | (109) | |
|
| ||
| p114RhoGEF (ArhGEF18) | Cell-Cell adhesion | (43) |
|
| ||
| Trio | Intermediate filaments | (147) |
|
| ||
| PDZRhoGEF (ArhGEF11) | Cell-ECM adhesion | (148) |
|
| ||
| GAPs | ||
|
| ||
| p190RhoGAP | Cell-ECM adhesion | (149) |
|
| ||
| DLC1 | Cell-ECM adhesion | (44) |
| Cell-Cell adhesion | (150) | |
|
| ||
| Myo-IXA | Cell-Cell adhesion | (54) |
(151)