Table 1.

Ventilation times, PIPs, and ventilation rates of all groups with terminal arterial blood gases and pH for all groups surviving the 2-h ventilation protocol

Treatment	PIP, cmH2O	Vent. Time, min	PaO, mmHg	PaCO2, mmHg	pH	Vent. Rate, breaths/min
NV	10	11.2 ± 1.2	211 ± 11	36.0 ± 1.2	7.28 ± 0.01	110
Low PIP	10	60	293 ± 7	34.5 ± 2.4	7.33 ± 0.01	110 ± 2
PIP40	40	60	466 ± 14*	27.6 ± 1.1	7.35 ± 0.01	28.3 ± 0.5
PIP40 OGG1	40	60	499 ± 8*	21.6 ± 0.3*	7.43 ± 0.02*	29.6 ± 0.4
PIP40	40	120	344 ± 4	26.3 ± 0.5	7.36 ± 0.01	28.3 ± 0.3
PIP40 OGG1	40	120	448 ± 21	20.4 ± 0.6†	7.35 ± 0.01	29.7 ± 2.4
PIP50	50	96.6 ± 0.7	NM	NM	NM	25.6 ± 0.2
PIP50 OGG1	50	120	331 ± 11	18.8 ± 0.6†	7.29 ± 0	25.8 ± 0.2

Applicable values are means ± SE.

^*P < 0.05 vs. no ventilation (NV) group;

^†P < 0.05 vs. NV and low-peak-inspiratory-pressure (PIP) group. Vent, ventilation; OGG1, 8-oxoguanine-DNA glycosylase 1; NM, not measured.