FIGURE 7.

Expression profile of canonical FZD receptors and LRP co-receptors is assessed upon overexpression of PITX2 isoforms in both SKOV-3 and OAW-42 cells. a, PITX2A, -B, and -C constructs are transiently transfected, and the relative expressions of FZD2,-3, -4, and -9 and LRP5 and LRP6 are analyzed by Q-PCR in SKOV-3 (a) and OAW-42 (b) cells. Here, pcDNA3.1 empty vector-transfected cells are indicated as control. The comparative expression is indicated as change in fold in the y axis (mean ± S.E.). * represents p < 0.05.