TABLE 2.

Catalytic efficiency of the Dbl proteins represented as fold activation

The catalytic efficiencies, calculated as fold activation, are divided into the following five groups according to Fig. 3: high (fold activation >10,000; black); intermediate (fold activation between 10,000 and 100; 75% gray); low (fold activation between 100 and 20; 50% gray); inefficient (fold activation between 20 and 5; 20% gray); and inactive (fold activation <5; white). Fold activation was obtained by dividing the k_obs values of GEF reactions by the k_obs values of the intrinsic reactions (Fig. 1).