Table 3. Evaluation of 8-hydroxydeoxyguanosine in the small intestine.
Group | 8-OHdG-positive cells* |
---|---|
Untreated° | 21.9±0.8 |
Histamine# | 21.4±1.5 |
Untreated-5 Gy§ | 46.7±4.9a |
Histamine-5 Gyˆ | 7.5±0.8a,b |
The percentage of 8-hydroxydeoxyguanosine (8-OHdG) immunoreactivity in cryptal cells expressed as mean ± SEM of 10 fields examined.
Representative of small intestines from at least eight saline-treated rats.
Representative of small intestines from at least eight 0.1 mg/kg.day histamine-treated rats;
Representative of small intestines from at least eight saline-treated and 5 Gy-irradiated rats;
Representative of small intestines from at least eight histamine-treated and 5 Gy-irradiated rats.
P<0.001 vs untreated,
P<0.001 vs untreated-5 Gy (ANOVA and Tukey Post test).