Table 1.
Treatment status, health status, and demographic features of subject who did and did not receive KRAS testing as part of their clinical care for colorectal cancer. P-values are unadjusted, from chi-square tests.
| Characteristic | Value | Tested | Not Tested | p-value | Characteristic | Value | Tested | Not Tested | p-value |
|---|---|---|---|---|---|---|---|---|---|
| Chemotherapy Regimens | 0 | 13 | 171 | <.0001 | Race | White | 306 | 520 | <.0001 |
| 1 | 28 | 146 | Asian | 42 | 52 | ||||
| 2 | 75 | 99 | Black | 37 | 90 | ||||
| 3 | 117 | 53 | Pacific Is. | 13 | 11 | ||||
| 4 | 80 | 49 | Am. Indian | 2 | 4 | ||||
| >5 | 264 | 93 | Other | 10 | 31 | ||||
| Unknown | 15 | 55 | |||||||
|
| |||||||||
| Surgery1 | No | 105 | 351 | <.0001 | Ethnicity | Not Hispanic | 319 | 592 | 0.0984 |
| Yes | 322 | 410 | Hispanic | 27 | 45 | ||||
|
| |||||||||
| Referral to Med. Oncology | No | 5 | 166 | <.0001 | Gender | Male | 222 | 379 | 0.1368 |
| Yes | 407 | 610 | Female | 205 | 381 | ||||
|
| |||||||||
| BMI Category | <20 | 17 | 61 | <.0001 | Household Income | < $40K | 95 | 221 | 0.0024 |
| 20-24 | 89 | 165 | $40K - $59K | 142 | 263 | ||||
| 25-29 | 122 | 182 | $60K - $79K | 90 | 141 | ||||
| ≥ 30 | 114 | 150 | ≥ $80K | 63 | 107 | ||||
|
| |||||||||
| Age at diagnosis, years | < 50 | 63 | 75 | <.0001 | % High School Education | < 50% | 4 | 12 | <.0001 |
| 50-59 | 124 | 110 | 50-69% | 36 | 63 | ||||
| 60-69 | 143 | 149 | 70-89% | 197 | 383 | ||||
| 70-79 | 73 | 230 | ≥ 90% | 166 | 260 | ||||
| ≥ 80 | 22 | 199 | |||||||
|
| |||||||||
| Charlson co-morbidity Index | 0 | 291 | 356 | <.0001 | Year of Metastatic Diagnosis | 2006 | 50 | 211 | <.0001 |
| 1 | 170 | 176 | 2007 | 123 | 228 | ||||
| 2 | 54 | 80 | 2008 | 179 | 194 | ||||
| 3 | 12 | 18 | 2009 | 93 | 110 | ||||
|
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| 4 | 8 | 13 | Medicare | No | 274 | 581 | <.0001 | ||
| ≥ 5 | 2 | 8 | Yes | 150 | 183 | ||||
|
| |||||||||
| Any EGFR inhibitor | No | 262 | 674 | <.0001 | Organization | A | 44 | 57 | <.0001 |
| Yes | 164 | 88 | B | 170 | 256 | ||||
|
|
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| Survival Interval, years (if deceased) | 0.5 | 28 | 438 | 0.0010 | C | 57 | 92 | ||
| 0.5–1 | 36 | 94 | D | 66 | 127 | ||||
| 1 – 2 | 73 | 131 | E | 37 | 87 | ||||
| ≥ 2 | 241 | 147 | F | 18 | 44 | ||||
|
|
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| Family History of Cancer | No | 129 | 220 | <.0001 | G | 37 | 96 | ||
|
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| Yes | 214 | 296 | Cancer Stage | III | 120 | 146 | <.0001 | ||
| Unk | 86 | 243 | IV | 313 | 609 | ||||
Colectomy or hemicolectomy