Fig. 2.
Proposed role of P450 enzyme system in the degradation of lindane by P. chrysosporium BKM-F-1767 (derived with permission from John Wiley & Sons Ltd: Mougin et al. 1996). Non-involvement of LiPs and MnPs in the biodegradation process is shown on the right hand side. Under both ligninolytic and non-ligninolytic culture conditions, P450s were shown to be involved in the successive dechlorination and oxygenation steps based on metabolite identification and use of the P450 inhibitor 1-aminobenzotriazole (ABT). The P450(s) involvement and the inhibitory effect of ABT at the respective steps are indicated.