Table II. Peroxisomal proteins found in human sperm.
| Access number | Protein name | Gene | Function | Localization | Descriptions |
|---|---|---|---|---|---|
| O14734 | Acyl-coenzyme A thioesterase 8 | ACOT8 | Fatty acid oxidation | Peroxisomal matrix | Present study |
| P09110 | 3-ketoacyl-CoA thiolase, peroxisomal | ACAA1 | Fatty acid beta-oxidation; fatty acid synthesis | Peroxisomal matrix | Present study |
| P51659 | Peroxisomal multifunctional enzyme type 2 | HSD17B4 | Fatty acid beta-oxidation; fatty acid synthesis | Peroxisomal matrix | Baker et al., 2007 (4) |
| Q9UJ83 | 2-hydroxyacyl-CoA lyase 1 | HACL1 | Fatty acid alpha-oxidation | Peroxisomal matrix | Present study |
| Q13907 | Isopentenyl-diphosphate delta-isomerase 1 | IDI1 | Isoprenoid and cholesterol biosynthesis | Peroxisomal matrix | Present study |
| Q15126 | Phosphomevalonate kinase | PMVK | Isoprenoid and cholesterol biosynthesis | Peroxisomal matrix | Present study |
| Q9UBQ7 | Glyoxylate reductase/hydroxypyruvate reductase | GRHPR | Glyoxylate metabolism | Peroxisomal matrix | Present study; Baker et al., 2007 (4) |
| O75192 | Peroxisomal membrane protein 11A | PEX11A | Peroxisome division/proliferation | Peroxisomal membrane | Gu et al., 2011 (8) |
| O96011 | Peroxisomal membrane protein 11B | PEX11B | Peroxisome division/proliferation | Peroxisomal membrane | Present study |
| Q96HA9 | Peroxisomal membrane protein 11C | PEX11G | Peroxisome organization | Peroxisomal membrane | Present study |
| O00623 | Peroxisomal assembly protein 12 | PEX12 | Peroxisomal protein import | Peroxisomal membrane | Gu et al., 2011 (8) |
| Q9Y5Y5 | Peroxisomal membrane protein PEX16 | PEX16 | Peroxisome membrane biogenesis/assembly | Peroxisomal membrane | Present study |
| O00116 | Alkyldihydroxyacetonephosphate synthase, peroxisomal | AGPS | Etherlipid biosynthesis | Peroxisomal membrane and matrix | Present study |
| Q6YN16 | Hydroxysteroid dehydrogenase-like protein 2 | HSDL2 | Unknown | Peroxisome | Present study |
| Q8NBU5 | ATPase family AAA domain-containing protein 1 | ATAD1 | Unknown | Peroxisome | Present study |
| O75521 | Peroxisomal 3,2-trans-enoyl-CoA isomerase | ECI2 | Fatty acid synthesis | Peroxisomal matrix (and mitochondria) | Baker et al., 2007 (4) |
| Q13011 | Delta(3,5)-delta(2,4)-dienoyl-CoA isomerase | ECH1 | Fatty acid beta-oxidation; fatty acid synthesis | Peroxisomal matrix (and mitochondria) | Present study; Baker et al., 2007 (4); Martínez-Heredia et al., 2006 (3) |
| P43155 | Carnitine O-acetyltransferase | CRAT | Fatty acid oxidation | Peroxisomal matrix (and mitochondria) | Present study |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | IDH1 | Glyoxylate metabolism; fatty acid biosynthesis | Peroxisomal matrix (and cytoplasm) | Present study; Baker et al., 2007 (4) |
| Q9Y3D6 | FIS1 homolog | FIS1 | Peroxisomal fission | Peroxisomal membrane (and mitochondria) | Present study |
The first 15 proteins have a exclusive peroxisomal localization, whereas the last 5 proteins can be peroxisomal and/or mitochondrial/ cytoplasmatic.