Table 9.
Sensitivity, specificity, PPV, and NPV for probability cut-off points
| |
Method 1 |
Method 2 |
|---|---|---|
| Cut-point 1 (MLE) | Probability .45 | Probability .41 |
| Sensitivity |
52.1 % |
18.3 % |
| Specificity |
74.0 % |
96.2 % |
| PPV |
61.8 % |
55.3 % |
| NPV |
65.7% |
81.9 % |
| Cut-point 2 (Sen. 90%) |
Probability .33 |
Probability .13 |
| Sensitivity |
90.9 % |
89.8 % |
| Specificity |
17.6 % |
28.0 % |
| PPV |
47.1 % |
20.6 % |
| NPV |
70.5 % |
91.3 % |
| Cut-point 3 (Sen. 80%) |
Probability .37 |
Probability .15 |
| Sensitivity |
80.5 % |
78.2 % |
| Specificity |
37.1 % |
45.0 % |
| PPV |
50.9 % |
28.7 % |
| NPV |
70.2 % |
88.8 % |
| Cut-point 4 (Spc. 80%) |
Probability .48 |
Probability .23 |
| Sensitivity |
39.9 % |
45.8 % |
| Specificity |
81.4 % |
79.5 % |
| PPV |
63.4 % |
36.7 % |
| NPV | 62.6 % | 85.0 % |