Figure 3.

Phylogenetic trees of Greater Toronto Area human adenovirus species B, C and D hexon gene, hypervariable region 7 (HVR 7), nucleotide sequences. (a). HAdV B species and corresponding serotypes (3, 11, 21), (b). HAdV C species and corresponding serotypes (1, 2, 5, 6), and (c). HAdV D species and corresponding serotype (17). Reference sequences representing known serotypes are indicated by a solid circle. Multiple sequences alignments and phylogenetic trees were constructed using ClustalW and the maximum likelihood method algorithm within MEGA 5.05 software, respectively. Tree topology was supported by bootstrap analysis with 1000 pseudo replicate datasets. The scale bar represents the number of nucleotide substitutions per site between close relatives.